Tuberous sclerosis presenting as cardiac arrhythmia.

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Tuberous sclerosis and cardiac arrhythmia in three Zulu patients.

Cardiac arrhythmias, in the form of multiple atrial or ventricular extrasystoles together with various types of conduction defect, occurred in three Zulu patients with tuberous sclerosis. Probably this association occurs more often than has been suspected.

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Cardiac tumours were identified on ultrasonography in fetal or early postnatal life in five infants. Tuberous sclerosis was subsequently diagnosed in all five. Only one infant required operation. Regression of the tumour occurred in three. No infant had hypomelanotic macules at birth, and they took up to two years to appear.

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Tuberous sclerosis complex presenting as pulmonary lymphangioleiomyomatosis - a clinicoradiological diagnosis

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Tuberous sclerosis complex presenting as a pulmonary solitary nodule.

Sir: Tuberous sclerosis complex (TSC) is a rare autosomal dominant disease characterized by hamartomatous lesions in several organs. TSC-related pulmonary manifestations comprise several pathological conditions, such as lymphangioleiomyomatosis (LAM), multifocal micronodular pneumocyte hyperplasia (MMPH), clear cell sugar tumour, angiomyolipoma and micronodular ⁄ interstitial clear cell LAM-lik...

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ژورنال

عنوان ژورنال: Heart

سال: 1968

ISSN: 1355-6037

DOI: 10.1136/hrt.30.1.132